The Vacation Solution
After being forced to take a vacation by President Siebert, Sheldon decides to spend it working with Amy in her neurobiology lab. However he refuses to do even basic work for Amy properly, such as cleaning beakers or counting bacterial spores, and instead forces her to allow him to do brain dissection. When Amy eventually allows Sheldon to perform brain dissection, he cuts his thumb accidentally and faints after seeing it bleed. Meanwhile, Bernadette’s father wants Howard to sign a prenuptial agreement. Howard, unwilling to sign any prenup, is upset that Bernadette did not tell him directly about the prenup. Later Penny confronts both Sheldon and Howard at the Cheesecake Factory bar for their behavior towards their girlfriends. The next day, Sheldon goes over to Amy’s lab again to apologize for his behavior the previous day. She then invites him to work with her again, but gives him the same basic work of cleaning beakers. Meanwhile, Bernadette tells Howard that her father is insistent on him signing the prenup, at which Howard says that he would talk it out with her father. But when Bernadette reveals that her father is a far right ideologue who hates Jews, Howard decides to put off the talk until he is in the space.
Title reference: Suddenly forced to take his vacation time, Sheldon decides to go to work with Amy in her biology lab.